| HEAD COACH | YEARS | OVERALL | CONFERENCE |
| Jim Catanzaro | 2009-22 (14) | 82-53 (.607) | 62-34 (.646) |
| Mike Dau (Hall of Fame) | 1966-91 (25) | 80-126-3 (.390) | 35-46-1 (.433) |
| Ralph Jones (Hall of Fame) | 1933-48 (13) | 52-31-10 (.609) | 9-4-1 (.679) |
| Chad Eisele | 2000-04 (5) | 31-20-0 (.607) | 28-16 (.636) |
| Burt E. Kennedy | 1908-13 (6) | 29-6-5 (.788) | |
| Nick Wasylik (Hall of Fame) | 1958-65 (8) | 22-38-2 (.371) | 7-24-1 (.234) |
| Walter Lemm (Hall of Fame) | 1951-52, 1957 (3) | 17-6-1 (.729) | 13-2-1 (.844) |
| Brent Becker | 2005-08 (4) | 17-23 (.425) | 16-20 (.444) |
| Clarence Herschberger | 1902-04 (3) | 13-10-2 (.560) | |
| Floyd L. Brown | 1924-28 (5) | 13-17-7 (.446) | |
| Randy Moore | 1995-99 (5) | 13-34-0 (.277) | 12-28 (.300) |
| Ira MacIntosh (Hall of Fame) | 1929-32 (4) | 11-11-6 (.500) | |
| Ralph Glaze | 1921-23 (3) | 10-12-3 (.460) | |
| James A. Vaughan | 1905-06 (2) | 9-7-0 (.563) | |
| Alvin Hanke (Hall of Fame) | 1954-56 (3) | 9-12-3 (.438) | 9-8-2 (.526) |
| John Breen (Hall of Fame) | 1949-51 (3) | 9-13-2 (.417) | 9-6 (.600) |
| S. Randall Derby | 1919-20 (2) | 8-6-2 (.563) | |
| Maury Waugh | 1992-94 (3) | 6-21-0 (.222) | 4-17 (.190) |
| D.H. Jackson | 1899-00 (2) | 5-6-2 (.462) | |
| R.E. Brumbaugh | 1907 (1) | 4-1-1 (.750) | |
| Ira T. Carruthers | 1914 (1) | 3-5-0 (.375) | |
| E.J. Mather | 1916-18 (3) | 3-13-0 (.188) | |
| R.W. Thacker | 1917 (1) | 2-4-0 (.333) | |
| Other | 1882-98 (12) | 42-34-6 (.549) |